Critical Illness Polyneuropathy with Generalized Myoclonus

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Nerve excitability changes in critical illness polyneuropathy.

Patients in intensive care units frequently suffer muscle weakness and atrophy due to critical illness polyneuropathy (CIP), an axonal neuropathy associated with systemic inflammatory response syndrome and multiple organ failure. CIP is a frequent and serious complication of intensive care that delays weaning from mechanical ventilation and increases mortality. The pathogenesis of CIP is not we...

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Clinical review: Critical illness polyneuropathy and myopathy

Critical illness polyneuropathy (CIP) and myopathy (CIM) are major complications of severe critical illness and its management. CIP/CIM prolongs weaning from mechanical ventilation and physical rehabilitation since both limb and respiratory muscles can be affected. Among many risk factors implicated, sepsis, systemic inflammatory response syndrome, and multiple organ failure appear to play a cr...

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Approach to critical illness polyneuropathy and myopathy.

A newly acquired neuromuscular cause of weakness has been found in 25-85% of critically ill patients. Three distinct entities have been identified: (1) critical illness polyneuropathy (CIP); (2) acute myopathy of intensive care (itself with three subtypes); and (3) a syndrome with features of both 1 and 2 (called critical illness myopathy and/or neuropathy or CRIMYNE). CIP is primarily a distal...

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Management of critical illness polyneuropathy and myopathy.

A syndrome of generalized weakness, areflexia, and difficulty with weaning from a ventilator is a common clinical presentation in the critically ill patient, especially in the setting of sepsis, multiorgan failure, and hyperglycemia. At first believed to be a manifestation of nerve (critical illness neuropathy, CIN) or muscle (critical illness myopathy, CIM) dysfunction, our current conceptuali...

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Critical Illness Polyneuropathy in Patients With Major Burn Injuries

OBJECTIVE Critical illness polyneuropathy in burn patients is an underreported condition. It is associated with high mortality rates and prolonged hospital stay and rehabilitation. This study aims to further define the cause and outcome of critical illness polyneuropathy following major burn injuries. METHODS A retrospective review of all burn patients with neuropathy that presented to Royal ...

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ژورنال

عنوان ژورنال: Turkiye Klinikleri Journal of Case Reports

سال: 2020

ISSN: 2147-9291

DOI: 10.5336/caserep.2020-76038